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Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
[In vitro antifungal activity of mercurobutol]
1Unité de Mycologie, Institut Pasteur, Paris, France.
Abstract:
Mercurobutol, in its commercial form, exhibits fungistatic and fungicidal activities against both yeasts: Candida albicans, C. tropicalis, Torulopsis glabrata, Pityrosporum spp., and filamentous fungi: dermatophytes, Aspergillus fumigatus, mainly saprophytic or potentially pathogenic fungi of the cutaneo-mucous flora. Minimal inhibitory concentrations on this antiseptic indicate a high susceptibility of the species tested, that could justify the enlargement of the indication of the drug to the complementary treatment of most cutaneous mycosis.
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