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Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
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Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
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Pleura of the Lungs01:13

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
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Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...

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Updated: May 24, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
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Published on: April 21, 2022

[Malignant pleural mesothelioma with multiple nodules].

Michiko Asano1, Kenichi Gemba, Nobukazu Fujimoto

  • 1Department of Respiratory Medicine, Okayama Rosai Hospital.

Nihon Kokyuki Gakkai Zasshi = the Journal of the Japanese Respiratory Society
|February 23, 2012
PubMed
Summary

This case report details a rare instance of malignant pleural mesothelioma with unusual CT findings. Chemotherapy effectively reduced tumor size and pleural effusion in a 62-year-old man.

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Area of Science:

  • Oncology
  • Pulmonology
  • Radiology

Background:

  • Malignant pleural mesothelioma is a rare cancer primarily affecting the pleura.
  • Diagnosis often relies on imaging and histopathology, but presentations can vary.

Observation:

  • A 62-year-old man presented with left chest pain and left pleural effusion.
  • Chest CT revealed multiple left parietal pleural nodules and effusion, atypical for initial presentation.
  • Thoracoscopic examination and immunohistological analysis confirmed biphasic malignant pleural mesothelioma.

Findings:

  • Pathological examination of a parietal nodular mass confirmed biphasic malignant pleural mesothelioma.
  • Chemotherapy with carboplatin and pemetrexed led to a reduction in tumor size and pleural effusion.

Implications:

  • This case highlights the importance of considering malignant pleural mesothelioma even with atypical CT findings.
  • The findings suggest that standard chemotherapy regimens can be effective in managing this rare condition.
  • Further research into rare presentations of malignant pleural mesothelioma is warranted.