Genesis of ultrasonic microbubbles: a quick historical overview
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Updated: May 24, 2026

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
Published on: May 9, 2021
Marianna Karamanou1, Theodore G Papaioannou, Christodoulos Stefanadis
1History of Medicine Department, Medical School, University of Athens, Greece. mariannakaramanou@yahoo.com
Abstract:
Microbubbles were the subject of numerous experiments and theoretical analysis over the past 100 years. Linked with the discovery and evolution of ultrasound, they were considered to be excellent echoenhancers. From the theories on acoustic waves in antiquity and the discovery of ultrasound, to the genesis of microbubbles around 1968, in our paper we trace the magnificent story of these "magical" bubbles.
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