Related Experiment Video
Updated: May 24, 2026
08:19
Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
Published on: May 9, 2021
Genesis of ultrasonic microbubbles: a quick historical overview
Marianna Karamanou1, Theodore G Papaioannou, Christodoulos Stefanadis
1History of Medicine Department, Medical School, University of Athens, Greece. mariannakaramanou@yahoo.com
Current Pharmaceutical Design
|February 23, 2012
Summary
Microbubbles, crucial for ultrasound imaging, have been studied for a century. This paper chronicles their fascinating history and development as effective echoenhancers.
Area of Science:
- Acoustics and Biomedical Imaging
- Materials Science and Nanotechnology
Background:
- Historical context of acoustic wave theories and ultrasound discovery.
- Evolution of microbubble research alongside ultrasound technology.
- The genesis of microbubbles as a concept around 1968.
Observation:
- Microbubbles function as effective echoenhancers in ultrasound.
- Their development is intrinsically linked to advancements in ultrasound technology.
Findings:
- A comprehensive historical review of microbubble research spanning 100 years.
- Tracing the scientific journey from early acoustic theories to modern microbubble applications.
- Highlighting the pivotal role of microbubbles in ultrasound imaging.
Implications:
- Understanding the historical trajectory of microbubbles enhances future research directions.
- Appreciation for the interdisciplinary nature of microbubble development.
- Potential for novel applications in diagnostics and therapeutics.
Related Concept Videos
01:28History of Microbiology
Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
01:17Ultrasonography
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
During an ultrasonography procedure, a handheld device called a...
01:13Excess Pressure Inside a Drop and a Bubble
The shape of a small drop of liquid can be considered spherical, neglecting the effect of gravity. This drop can further be considered as two equal hemispherical drops put together due to surface tension. The forces acting on the spherical drop are due to the pressure of the liquid inside the drop, the pressure due to air outside the drop, and the force due to the surface tension acting on the two hemispherical drops.