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Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a

Ryota Niikura1, Naoyoshi Nagata, Junichi Akiyama

  • 1Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Tokyo, Japan.

International Journal of Colorectal Disease
|February 23, 2012
PubMed

Insights

Identifying risk factors for colonic diverticular bleeding is crucial. This study found that a large number of diverticula, hypertension, ischemic heart disease, and chronic renal failure are significant risk factors for diverticular bleeding.

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Epidemiology

Background:

  • Colonic diverticular bleeding is a significant cause of lower gastrointestinal bleeding.
  • Limited research exists on the specific risk factors contributing to diverticular bleeding.

Purpose of the Study:

  • To identify and analyze the independent risk factors associated with colonic diverticular bleeding.
  • To provide new insights into the etiology of diverticular bleeding.

Main Methods:

  • A prospective case-control study comparing patients with diverticular bleeding (cases) to those with diverticulosis (controls).
  • Data collected via questionnaires on habits, comorbidities, medications, and symptoms.
  • Colonoscopy used for diagnosis; logistic regression models employed to determine odds ratios (OR) and 95% confidence intervals (CI).

Main Results:

  • Analysis included 254 patients (45 with diverticular bleeding, 209 with diverticulosis).
  • Independent risk factors identified: cluster diverticula (OR=4.0), hypertension (OR=2.2), ischemic heart disease (OR=2.4), and chronic renal failure (OR=6.4).

Conclusions:

  • A high burden of diverticula, hypertension, and arteriosclerotic conditions like ischemic heart disease and chronic renal failure are key risk factors for diverticular bleeding.
  • This research contributes novel information to the understanding of risk factors for diverticular bleeding.
Abstract

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