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Properties of xyloglucan hydrogel as the biomedical sustained-release carriers
1Key Laboratory of Pesticide and Chemical Biology (Ministry of Education), College of Chemistry, Central China Normal University, Wuhan, People's Republic of China.
Abstract:
This study introduces an easy method of preparing xyloglucan hydrogel from xyloglucan, which is purified from tamarind seed gum. Xyloglucan hydrogel was prepared in 2 wt% solution by treating with β-galactosidase. Physical and chemical properties (molecular mass, size and viscosity) of xyloglucan hydrogel and xyloglucan solution were tested for a comparison. Experiments of drug release in vitro and in vivo were operated to investigate the potentialities of xyloglucan hydrogel as the biomedical sustained-release carriers for drug delivery system.
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