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Updated: May 24, 2026

Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test
Published on: January 15, 2010
[Parkinson's disease. Perioperative management and anesthesia]
1Klinik und Poliklinik für Neurologie, Rheinische Friedrich-Wilhelms-Universität, DZNE - Deutsches Zentrum für Neurodegenerative Erkrankungen, Bonn, Deutschland. wuellner@uni-bonn.de
Abstract:
Approximately 10,000-15,000 Parkinson's disease (PD) patients per year undergo surgery in Germany. The demographic developments along with further surgical progress and procedural refinements will lead to increasing numbers of PD patients in the operating theatre (OR). There are several perioperative risk factors for PD patients, they more often require prolonged intensive care treatment and warrant particular anesthesiological attention with regard to the choice of drugs and equipment. Careful evaluation of concomitant diseases, maintenance of oral Parkinson therapeutic drugs up to the time of surgery and continuous perioperative dopaminergic therapy are key factors for reducing postoperative morbidity in PD patients undergoing surgery.
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