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Genome-wide Gene Deletions in Streptococcus sanguinis by High Throughput PCR
14:07

Genome-wide Gene Deletions in Streptococcus sanguinis by High Throughput PCR

Published on: November 23, 2012

Genome-wide essential gene identification in Streptococcus sanguinis

Ping Xu1, Xiuchun Ge, Lei Chen

  • 1Philips Institute of Oral and Craniofacial Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, USA. pxu@vcu.edu

Scientific Reports
|February 23, 2012
PubMed
Summary

Identifying essential genes in bacterial pathogens like Streptococcus sanguinis is key for drug discovery and synthetic biology. This study reveals essential genes fall into three core functions: cell envelope, energy, and genetic information processing.

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