Related Experiment Video
Updated: May 24, 2026

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System
Published on: July 2, 2020
Hyperthermic effects of dissipative structures of magnetic nanoparticles in large alternating magnetic fields
Hiroaki Mamiya1, Balachandran Jeyadevan
1National Institute for Materials Science, Tsukuba 305-0047, Japan. MAMIYA.Hiroaki@nims.go.jp
Abstract:
Targeted hyperthermia treatment using magnetic nanoparticles is a promising cancer therapy. However, the mechanisms of heat dissipation in the large alternating magnetic field used during such treatment have not been clarified. In this study, we numerically compared the magnetic loss in rotatable nanoparticles in aqueous media with that of non-rotatable nanoparticles anchored to localised structures. In the former, the relaxation loss in superparamagnetic nanoparticles has a secondary maximum because of slow rotation of the magnetic easy axis of each nanoparticle in the large field in addition to the known primary maximum caused by rapid Néel relaxation. Irradiation of rotatable ferromagnetic nanoparticles with a high-frequency axial field generates structures oriented in a longitudinal or planar direction irrespective of the free energy. Consequently, these dissipative structures significantly affect the conditions for maximum hysteresis loss. These findings shed new light on the design of targeted magnetic hyperthermia treatments.
More Related Videos
09:01Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
10:45Stable Aqueous Suspensions of Manganese Ferrite Clusters with Tunable Nanoscale Dimension and Composition
Published on: February 5, 2022
Related Concept Videos
Paramagnetism
Magnetic Fields
A magnetic field is defined by the force that a charged particle experiences...
Ferromagnetism
Diamagnetic Shielding of Nuclei: Local Diamagnetic Current
Atomic Nuclei: Nuclear Relaxation Processes
Diamagnetism
Diamagnetism was discovered by Anton Brugmans in 1778 when he observed that bismuth gets repelled by magnetic fields, thus theorizing that diamagnets get repelled by magnets.