Related Experiment Video
Updated: May 24, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Ventricular septal defect and associated complications
Tauseef Asma Chaudhry1, Muhammad Younas, Ahsan Baig
1Department of Paediatric Cardiology, Chaudhry Pervaiz Elahi Institute of Cardiology, Multan.
Insights
Perimembranous ventricular septal defects (VSD) are most common in children. Large VSDs frequently cause severe pulmonary hypertension, the most common complication, followed by aortic valve issues.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Defects
- Echocardiography
Background:
- Ventricular septal defects (VSD) are common congenital heart anomalies.
- Understanding the frequency and types of VSDs is crucial for effective management.
- Associated complications impact patient outcomes.
Purpose of the Study:
- To determine the frequency of various ventricular septal defect (VSD) types.
- To identify associated complications in a pediatric population.
- To analyze demographic data related to VSDs.
Main Methods:
- A cross-sectional descriptive study analyzed echocardiography data from children under 15.
- Data included age, gender, VSD type, and complications.
- SPSS version 11 was used for data analysis.
Main Results:
- 1276 isolated VSD cases were identified (25% of congenital heart disease patients).
- Perimembranous VSD was the most frequent type (79.3%).
- Severe pulmonary hypertension (22.4%), aortic valve prolapse (6.7%), and aortic regurgitation (5.2%) were common complications.
Conclusions:
- Perimembranous VSD is the predominant type.
- Large VSDs are strongly associated with severe pulmonary hypertension.
- Severe pulmonary hypertension, aortic valve prolapse, and aortic regurgitation are the most significant VSD complications.
Objective:
To determine the frequency of various types of ventricular septal defects (VSD) and associated complications in local paediatric population.
Methods:
A cross sectional descriptive study was conducted on children undergoing echocardiography in a single centre from January 2006 to December 2009 at Paediatric Cardiology Department, Ch. Pervaiz Elahi Institute of Cardiology Multan- Tertiary referral centre for paediatric and adult cardiac services in South Punjab. The data on all children below 15 years of age undergoing detailed transthoracic two-dimensional echo and Doppler studies was reviewed. Cases with isolated ventricular septal defects were studied for age of presentation, gender, type, and associated complications. The data was analyzed with SPSS 11 version.
Results:
A total of 5018 patients with congenital heart diseases underwent echocardiography during this period. A total of 1276 patients had isolated VSD (25%). Mean age was 3.1 +/- 3.64 years (range: 1 day to 15 years). Females were 440 (34.5%) and males were 836 (66.5%). Of 1276 patients, 1014 (79.3%) were Perimembranous type, 124 (9.8%) were muscular type, 85 (6.7%) were doubly committed subarterial type and 53 (4.2%) inlet VSD. Small, moderate and large VSDs were 428 (33.6%), 443 (34.7%) and 405 (31.7%) respectively. Severe pulmonary hypertension was noted in 286 (22.4%) cases. Aortic valve prolapse was present in 85 (6.7%) cases and varying degrees of aortic valve regurgitation was seen in 67 (5.2 %) patients. Right ventricular outflow tract obstruction was found in 21 (1.6%) cases. Left ventricular outflow tract obstruction was noted in 09 (0.7%) cases. Echo evidence of infective endocarditis was present in 06 (0.5%) patients.
Conclusion:
Perimembranous ventricular septal defect was found to be the commonest type of ventricular septal defect. Large ventricular septal defects usually lead to severe pulmonary hypertension. Severe pulmonary hypertension was the commonest complication followed by Aortic Valve Prolapse and Aortic Regurgitation. Rest of the complications were rare.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Regurgitation I: Introduction
Cardiomyopathy V: Interprofessional Care
Mitral Valve Prolapse I: Introduction
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy II: Dilated Cardiomyopathy
