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Related Experiment Video

Updated: May 24, 2026

Local Hyperthermia for Warts Treatment

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Published on: November 8, 2024

Can white spot lesions be treated effectively?

Mehmet Akin¹, Faruk Ayhan Basciftci

¹Department of Orthodontics, Faculty of Dentistry, University of Selçuk, Konya, Turkey. mehmetakin07@hotmail.com

The Angle Orthodontist

|February 24, 2012

Summary

Microabrasion and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) show promise for treating white spot lesions. Microabrasion yielded the highest success rate, while CPP-ACP outperformed fluoride rinse for post-orthodontic remineralization.

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Area of Science:

Dentistry
Orthodontics
Cariology

Background:

White spot lesions (WSLs) are common decalcified enamel defects following fixed orthodontic therapy.
Effective treatment strategies are needed to improve the aesthetic and structural integrity of affected enamel.

Purpose of the Study:

To compare the efficacy of sodium fluoride mouth rinse, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and the microabrasion technique in treating post-orthodontic WSLs.

Main Methods:

Eighty patients with 966 WSLs were divided into four groups: control (brushing only), sodium fluoride rinse, CPP-ACP (Tooth Mousse), and microabrasion (18% hydrochloric acid).
Treatments were administered over a specified period, with outcomes assessed for lesion area reduction and success rates.
Statistical analysis employed generalized linear mixed models and Tukey HSD tests at P < .05.

Main Results:

All treatment groups demonstrated a significant decrease in WSL area.
Microabrasion achieved the highest success rate (97%).
CPP-ACP showed a significantly higher success rate (58%) compared to sodium fluoride rinse (48%) and the control group (45%).

Conclusions:

CPP-ACP offers superior remineralization benefits compared to fluoride rinse for post-orthodontic WSLs.
Microabrasion is a highly effective method for the cosmetic enhancement of established white spot lesions.