Related Experiment Video
Updated: May 24, 2026

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
Published on: April 21, 2015
Viral infections in patients with inflammatory bowel disease on immunosuppressants
Tauseef Ali1, Laura Yun, David Shapiro
1Section of Gastroenterology, University of Oklahoma Health Sciences Center, Oklahoma City, USA. Tauseef-ali@ouhsc.edu
Abstract:
The use of immunosuppressant medications and biologics such as tumor necrosis factor alpha antagonists has revolutionized the treatment of inflammatory bowel disease. With increasing use of such agents, the risk of serious infections is a key safety concern for treated patients. Greater physician awareness about these potential infections is important to optimize patient outcomes through early recognition and potential preventive strategies. The authors present a comprehensive and concise review of clinically important viral infections associated with the inflammatory bowel disease therapy.
Related Concept Videos
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

