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Factors associated with early catheter-related complications in peritoneal dialysis

T Hryszko1, E Suchowierska, A Rydzewska-Rosolowska

  • 1Department of Nephrology and Transplantation, Medical University of Bialystok, Poland. tomhry@mp.pl

Advances in Medical Sciences
|February 24, 2012
PubMed

Insights

Delaying peritoneal dialysis (PD) initiation after catheter insertion reduces catheter-related complications (CRC). Early PD starts (1-13 days) showed significantly more CRC than late starts (≥14 days).

Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Peritoneal Dialysis

Background:

  • Peritoneal dialysis (PD) catheter insertion requires a healing period before dialysis initiation.
  • Current recommendations suggest delaying PD initiation for 10-14 days post-catheter insertion.

Purpose of the Study:

  • To investigate factors associated with catheter-related complications (CRC).
  • To compare CRC rates in patients starting PD early (1-13 days) versus late (≥14 days) after catheter implantation.

Main Methods:

  • Retrospective analysis of 97 patients undergoing PD.
  • Categorization into early start (ES) and late start (LS) groups based on PD initiation timing.
  • Analysis of CRC within 14 days of PD initiation.

Main Results:

  • Seventy percent of patients were in the early start group.
  • Significantly higher CRC rates in the ES group (31%) compared to the LS group (3%, p=0.01).
  • Mechanical CRC were significantly more frequent in ES (21%) vs. LS (0%, p=0.01); infectious CRC rates did not differ.
  • Time to PD initiation was the sole predictor of CRC (OR 0.80, p=0.001).

Conclusions:

  • Delaying PD initiation post-catheter insertion significantly reduces the risk of mechanical catheter-related complications.
  • Each day of delay in PD initiation decreases the odds of developing mechanical CRC.
Abstract

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