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Updated: May 24, 2026

A Computer-assisted Multi-electrode Patch-clamp System
Published on: October 18, 2013
Development of a versatile computer integrated control system for bioprocess controls
1Human Genome Sciences Inc., 9410 Key West Ave., Rockville, MD, 20850, U.S.A.
Abstract:
A general approach is described for the implementation of a networked multi-unit computer integrated control system. The use of data acquisition hardware and graphical programming tools alleviates tedious programming and maintains potency and flexibility. One application of the control system, the control of a mammalian cell perfusion culture based on a key nutrient glucose concentration, was demonstrated. The control system offers customized user interface for all process control parameters and allows the flexibility for continued improvement and implementation of new tailored functions. The temperature, pH, dissolved oxygen and glucose level were accurately controlled.
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