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Updated: May 24, 2026

Technique to Collect Fungiform (Taste) Papillae from Human Tongue
Published on: September 18, 2010
[A tongue biopsy led to the diagnosis]
M Brandstetter1, Y Matsuba, A Knopf
1Hals-Nasen-Ohrenklinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München. m.brandstetter@lrz.tum.de
Abstract:
A 76-year-old patient in otherwise good health presented with a 2-year history of bilateral painless submandibular swelling and macroglossia. A standard ENT examination revealed no additional symptoms. Tongue biopsy led to the diagnosis of amyloidosis, serum immunofixation identified AL amyloidosis and a kappa light chain gammopathy resulting from multiple myeloma as the underlying cause.
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