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Updated: May 24, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
A cognitive behaviour therapy (CBT) programme for anxiety following moderate-severe traumatic brain injury (TBI): two
Ming-Yun Hsieh1, Jennie Ponsford, Dana Wong
1School of Psychology and Psychiatry, Monash University, Melbourne, Australia.
Background:
CBT is a potentially effective treatment for anxiety disorders following TBI; however, empirical evidence has mainly come from clients with mild TBI. This paper describes a CBT-based anxiety treatment programme adapted for clients with more severe injuries. Two case studies are provided to illustrate the implementation of the programme, as a step toward larger scale testing of the programme's feasibility.
Methods And Procedures:
A manualised adapted CBT treatment manual was used to deliver CBT in a standardised manner to two clients, one with severe and one with moderate TBI. Outcome was evaluated using a single-subject design with repeated measures of anxiety, mood and coping style at pre- and post-CBT.
Results:
The two clients demonstrated positive treatment response on either a measure of anxiety or a continuous measure of distress. Although neither demonstrated a clinically significant change according to the primary outcome measure (Hospital Anxiety and Depression Scale), they showed significant change in at least one corroborated measure of anxiety.
Conclusions:
This study suggests the potential utility of the adapted CBT programme for clients with moderate-severe TBI. Limitations of the single case studies were discussed, while noting how they would be addressed in a follow-up randomised controlled trial.
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