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Updated: May 24, 2026

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
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Published on: January 5, 2016

α-Synuclein fate: proteasome or autophagy?

Simone Engelender1

  • 1Department of Pharmacology, The B. Rappaport Faculty of Medicine and Institute of Medical Research, Technion-Israel Institute of Technology, Haifa, Israel. simone@tx.technion.ac.il

Autophagy
|February 25, 2012
PubMed
Summary

USP9X deubiquitinates alpha-synuclein, influencing its degradation via proteasomal or autophagy pathways. Reduced USP9X in Parkinson disease brains suggests it

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