Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Ankle Joint01:10

Ankle Joint

The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The ARUTIS Study (Anglia Ruskin University Trial of the Intuitive System): a single-centre, double-masked randomised controlled crossover trial of precision tinted lenses for visual stress: study protocol for a randomised controlled trial.

Trials·2025
Same author

Precision, reliability and application of the Wilkins Rate of Reading Test.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2021
Same author

Neuromuscular Mimics of Entrapment Neuropathies of Upper Extremities.

Hand (New York, N.Y.)·2020
Same author

12 versus 24 h bed rest after acute ischemic stroke thrombolysis: a preliminary experience.

Journal of the neurological sciences·2019
Same author

Clinical Use of the Kannada and English Rate of Reading Tests.

Frontiers in psychology·2019
Same author

Neurohistiocytosis of the Cerebellum: A Rare Cause of Ataxia.

Movement disorders clinical practice·2018

Related Experiment Video

Updated: May 24, 2026

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

The Charcot joint: a modern neurologic perspective.

Kara A Chisholm1, James M Gilchrist

  • 1Department of Neurology, Rhode Island Hospital and Alpert Medical School of Brown University, Providence, RI 02903, USA.

Journal of Clinical Neuromuscular Disease
|February 25, 2012
PubMed
Summary

Charcot joint (Charcot neuroarthropathy) is a rare neurologic complication. Early detection and treatment are key to preventing chronic bone deformity in patients with peripheral neuropathy.

More Related Videos

An Anatomical Study of Nerves at Risk During Minimally Invasive Hallux Valgus Surgery
15:04

An Anatomical Study of Nerves at Risk During Minimally Invasive Hallux Valgus Surgery

Published on: February 17, 2018

Related Experiment Videos

Last Updated: May 24, 2026

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

An Anatomical Study of Nerves at Risk During Minimally Invasive Hallux Valgus Surgery
15:04

An Anatomical Study of Nerves at Risk During Minimally Invasive Hallux Valgus Surgery

Published on: February 17, 2018

Area of Science:

  • Neurology
  • Rheumatology
  • Orthopedics

Background:

  • Charcot neuroarthropathy, a condition described over 140 years ago, remains underrepresented in neurologic literature.
  • Neurologists are primary caregivers for patients with peripheral neuropathy, placing them in a key position for early diagnosis.

Observation:

  • This review discusses a recent case and details the history, epidemiology, pathophysiology, and clinical features of acute and chronic Charcot joint disease.
  • Emphasis is placed on the diagnostic value and limitations of imaging, with a proposed diagnostic algorithm.
  • Therapeutic strategies for both acute and chronic Charcot joints are reviewed, including a treatment algorithm.

Findings:

  • The study highlights the importance of imaging in diagnosing Charcot neuroarthropathy.
  • Diagnostic and treatment algorithms are proposed to aid clinicians.

Implications:

  • Enhancing neurologist awareness of Charcot neuroarthropathy can lead to earlier detection of the acute form.
  • Early intervention may reduce or prevent the progression to chronic bony deformation associated with Charcot joint disease.