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Nonsteroidal antiinflammatory agents. Part 20(3): Optically active thienyl-biphenylyl-hydroxypropionic acids
L Varoli1, S Burnelli, A Guarnieri
1Dipartimento di Scienze Farmaceutiche, Università di Bologna, Italia.
Die Pharmazie
|July 1, 1990
Abstract:
The optically active diastereometric erythro- and threo-3-thienyl-analogues 6a-d of 3-aryl-2-biphenylyl-3-hydroxy-propionic acids have been prepared. Some stereoisomers of 3-(3-thienyl)derivative 6b showed inhibition around 40% in the carrageenan-induced rat paw edema test.