Related Experiment Video
Updated: May 24, 2026
12:18
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
[Mild cognitive impairment: early detection and new perspectives]
S Mora-Simon1, R Garcia-Garcia, M V Perea-Bartolome
1Centro de Salud La Alamedilla, Salamanca, Espana. s_mora@usal.es
Revista De Neurologia
|February 25, 2012
Summary
Early detection of mild cognitive impairment (MCI) is crucial. Current screening tests often fail to accurately identify MCI, necessitating a careful selection and combination of tests for effective clinical diagnosis.
Area of Science:
- Neurology
- Gerontology
- Cognitive Science
Background:
- Mild cognitive impairment (MCI) is increasingly researched for early detection.
- Current definitions characterize MCI as cognitive impairment without functional decline, accompanied by subjective concern.
- Existing cognitive screening tests often misdiagnose MCI as dementia.
Purpose of the Study:
- To analyze cognitive screening tests for their suitability in clinical MCI detection.
- To evaluate tests based on current research and MCI diagnostic criteria.
Main Methods:
- Review and analysis of existing cognitive screening tests.
- Categorization of tests into general, specific, and MCI-subtype screening tests.
- Comparison of test performance against current MCI diagnostic criteria.
Main Results:
- Most available cognitive screening tests do not align with current MCI criteria.
- A significant gap exists between test capabilities and the accurate identification of MCI.
- Three categories of tests exist: general, specific, and MCI-subtype.
Conclusions:
- A careful selection of cognitive screening tests is essential for accurate MCI detection.
- Joint application of multiple, well-chosen tests is recommended for effective clinical practice.
- Future research should focus on developing and validating tests that meet current MCI diagnostic standards.
Related Concept Videos
01:30Dementia
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
The progression of dementia is generally gradual.
01:22Dementia l: Introduction
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
01:26Alzheimer's Disease: Overview
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
01:29Alzheimer Disease l: Introduction
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
01:30Cognitive Development During Adulthood
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
01:22Alzheimer's Disease: Treatment
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...