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A Murine Model of Group B Streptococcus Vaginal Colonization

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Published on: November 16, 2016

Beta-hemolytic Streptococcus spp. from horses: a retrospective study (2000-2010).

Erdal Erol¹, Stephan J Locke, Judy K Donahoe

¹University of Kentucky, Veterinary Diagnostic Laboratory, PO Box 14125, Lexington, KY 40512-4125, USA. erdal.erol@uky.edu

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

|February 25, 2012

Summary

This study analyzed beta-hemolytic streptococci in horses from 2000-2010. Streptococcus equi subsp. zooepidemicus was most common, with varied tissue distribution and general antimicrobial susceptibility observed.

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Area of Science:

Veterinary Microbiology
Equine Infectious Diseases
Antimicrobial Susceptibility Testing

Background:

Beta-hemolytic streptococci are significant pathogens in horses.
Understanding their distribution and antimicrobial resistance is crucial for effective treatment and disease management.

Purpose of the Study:

To comprehensively analyze the tissue/organ distribution of beta-hemolytic streptococci in horses.
To determine antimicrobial susceptibility patterns of isolated streptococci over a ten-year period.

Main Methods:

Retrospective analysis of 2,497 beta-hemolytic streptococci isolates from 2,391 equine cases (2000-2010).
Identification of bacterial species and their isolation sites.
Antimicrobial susceptibility testing using the Kirby-Bauer method.

Main Results:

Streptococcus equi subsp. zooepidemicus (72.0%) was the most frequent isolate, followed by Streptococcus dysgalactia subsp. equisimilis (21.3%).
S. equi subsp. equi primarily affected the respiratory tract and lymph nodes, while S. zooepidemicus and S. equisimilis showed broader tissue tropism, including reproductive and other organs.
Most isolates were susceptible to cephalothin, erythromycin, nitrofurantoin, penicillin, and ticarcillin/clavulanate; resistance to gentamicin and tetracycline emerged in S. equisimilis.

Conclusions:

Streptococcus equi subsp. zooepidemicus and Streptococcus dysgalactia subsp. equisimilis are major causes of streptococcal infections in horses, with distinct tissue tropisms.
Antimicrobial susceptibility remains generally favorable, but emerging resistance to specific agents like gentamicin and tetracycline in S. equisimilis warrants attention.
This study highlights the importance of S. equisimilis as a significant equine pathogen and provides valuable data for antimicrobial stewardship in equine practice.