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Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

Use of surgical sponge with running sutures for securing full-thickness skin grafts

Stamatis Sapountzis1, Achilleas Chantes, Ji Hoon Kim

  • 1Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, 166 Gumiro, Bundang, Gyeonggi, Seongnam 463-707, Republic of Korea.

ISRN Dermatology
|February 25, 2012
PubMed

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...