Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Dissociative Amnesia

Dissociative Amnesia

Dissociative amnesia is a complex psychological condition that manifests as an inability to recall personal information, often tied to traumatic or stressful events. Unlike general amnesia, individuals with this condition retain the ability to perform routine activities and procedural tasks, such as operating a phone or navigating public transportation, yet experience profound gaps in autobiographical memory. These lapses may encompass significant life events, such as suicide attempts or...

Amnesia

Amnesia

Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...

Transient Ischemic Attack l: Introduction

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

Dissociative Disorders

Dissociative Disorders

Dissociative disorders represent complex psychological conditions characterized by disruptions in consciousness, memory, identity, or perception. These disruptions cause individuals to experience a disconnection from their thoughts, emotions, and memories. The phenomenon is not merely an occasional lapse in attention but a profound alteration in mental functioning that can severely impact daily life.
Dissociative Fugue
A hallmark feature of dissociative disorders is the dissociative fugue...

Dementia l: Introduction

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...

Seizures l: Introduction

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Safety of migraine prophylaxis with calcitonin gene-related peptide monoclonal antibodies in comorbid chronic inflammatory central nervous system disease: A case series.

Headache·2026

Same author

Health and quality of life in patients with leg lymphedema during maintenance phase.

VASA. Zeitschrift fur Gefasskrankheiten·2026

Same author

Response to Letter to Editor: Headache After Sealing of Cerebrospinal Fluid Leaks in Patients With Spontaneous Intracranial Hypotension.

European journal of neurology·2026

Same author

Learnings from familial visual snow syndrome: A case series.

Headache·2026

Same author

ESTREL-Fatigue-association of levodopa with post-stroke fatigue.

European stroke journal·2026

Same author

Timing of Effect Onset After Restarting Anti CGRP-(Receptor)-Monoclonal Antibodies Following a Mandatory Cessation After One year of Use-A Single Center Retrospective Cohort Study.

Drug design, development and therapy·2026

Search research articles

Related Experiment Video

Updated: May 24, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Acute confusional migraine: our knowledge to date.

Sivan Schipper¹, Franz Riederer, Peter S Sándor

¹Headache & Pain Unit, Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, CH-8091, Zurich, Switzerland.

Expert Review of Neurotherapeutics

|February 28, 2012

Summary

Acute confusional migraine (ACM) is a rare migraine variant often underdiagnosed in children and adults. It presents as a confusional state with diverse neurological symptoms, requiring exclusion of other serious conditions.

More Related Videos

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

Related Experiment Videos

Last Updated: May 24, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

Area of Science:

Neurology
Pediatric Neurology
Neuroscience

Background:

Acute confusional migraine (ACM) is a rare variant of migraine.
It affects both children and adults, with prevalence in children ranging from 0.45% to 7.8%.
ACM is often underdiagnosed and requires exclusion of other serious neurological conditions.

Purpose of the Study:

To describe the characteristics of Acute Confusional Migraine.
To highlight diagnostic challenges and differential diagnoses.
To discuss the proposed pathomechanisms of ACM.

Main Methods:

Review of existing literature and clinical case studies.
Diagnostic criteria for ACM and differential diagnoses.
Analysis of symptoms, triggers, and potential underlying mechanisms.

Main Results:

ACM presents as a confusional state with varied cortical dysfunctions including speech difficulties, agitation, and amnesia.
Mild head trauma is a potential trigger in about half of cases.
Transient global amnesia is a key differential diagnosis.

Conclusions:

ACM is a diagnosis of exclusion, necessitating thorough clinical evaluation and exclusion of dangerous conditions.
The pathomechanism is hypothesized to involve cortical spreading depression affecting multiple brain regions.
Further research is needed to clarify the exact pathophysiology of ACM.