Related Experiment Video
Updated: May 24, 2026
07:06
Isolation and Quantification of Axonal mRNAs Using Porous Membrane Inserts and RTddPCR
Published on: February 6, 2026
Axonal mRNA translation: an unexpected link to axon survival and the mitochondrion
Nicolas Preitner1, John G Flanagan
1Department of Cell Biology and Program in Neuroscience, Harvard Medical School, Boston MA 02115, USA. nicolas_preitner@hms.harvard.edu
Neuron
|February 28, 2012
Abstract:
Localized mRNA translation plays roles in dendrites and axons, but the regulatory mechanisms and downstream pathways are not well understood. An article in Cell by Yoon et al. (2012) shows that lamin B2, well known as a nuclear protein, undergoes regulated synthesis in axons, promoting mitochondrial function and axon survival.
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