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Updated: May 24, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
Rheumatoid arthritis and the era of biologic therapy
Anshuman P Malaviya1, Andrew J K Ostör
1School of Clinical Medicine, University of Cambridge, Cambridge, UK. anshuman.malaviya@addenbrookes.nhs.uk
Abstract:
Biologic disease modifying anti-rheumatic drugs have transformed the management of rheumatoid arthritis (RA) since their introduction into clinical practice over a decade ago. Following large-scale clinical trials, a number of biologics, with different mechanisms of action, have been licensed for the condition. In this review, we will summarise the current evidence for biologic use in RA with an emphasis on their efficacy and tolerability. In addition, we will provide a commentary on the current limitations and unmet needs in this area and discuss the future of biologic intervention.
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