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Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

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Related Experiment Video

Updated: May 24, 2026

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development
09:43

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development

Published on: August 10, 2015

Continuous renal replacement therapy in children.

Scott M Sutherland1, Steven R Alexander2

  • 1Department of Pediatrics, Division of Nephrology, Stanford University Medical Center, 300 Pasteur Drive, Room G-306, Stanford, CA, 94035, USA. suthersm@stanford.edu.

Pediatric Nephrology (Berlin, Germany)
|February 28, 2012
PubMed
Summary
This summary is machine-generated.

Acute kidney injury (AKI) in children is increasingly complex. Continuous renal replacement therapy (CRRT) is now the standard treatment for critically ill pediatric patients with AKI, with evolving guidelines for its use.

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Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development
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Area of Science:

  • Pediatric Nephrology
  • Critical Care Medicine
  • Renal Replacement Therapy

Background:

  • Epidemiology of pediatric acute kidney injury (AKI) has evolved.
  • Pediatric AKI patients often present with comorbidities, fluid overload, and severe illness.
  • Continuous renal replacement therapy (CRRT) is the preferred management modality for pediatric AKI.

Purpose of the Study:

  • To provide a state-of-the-art review of pediatric CRRT.
  • To examine recent data on CRRT in critically ill children.
  • To cover technical aspects, indications, timing, dosing, and outcomes of pediatric CRRT.

Main Methods:

  • Literature review of recent data on pediatric CRRT.
  • Analysis of technical aspects of CRRT delivery in children.
  • Examination of current evidence on CRRT indications, initiation, dosing, and outcomes.

Main Results:

  • CRRT is the established treatment for severe pediatric AKI.
  • Recent data informs best practices for CRRT in critically ill children.
  • Specifics on timing, dosing, and technical considerations are crucial for optimal outcomes.

Conclusions:

  • Pediatric CRRT management requires a comprehensive understanding of technical aspects and recent evidence.
  • Optimizing CRRT initiation, dosing, and technical delivery improves outcomes in critically ill children with AKI.
  • This review synthesizes current knowledge to guide clinical practice in pediatric CRRT.