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Updated: May 24, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Causal relationship between periodontitis and chronic obstructive pulmonary disease
1Department of Periodontics, Panineeya Maha Vidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Andhra Pradesh, India.
Journal of Indian Society of Periodontology
|February 28, 2012
Summary
Periodontal disease is significantly associated with chronic obstructive pulmonary disease (COPD). This suggests that periodontitis may be a risk factor for developing COPD, highlighting the link between oral health and respiratory conditions.
Area of Science:
- Oral health and systemic disease research
- Pulmonary medicine
- Periodontology
Background:
- Emerging evidence links oral infections, particularly periodontitis, to systemic disease progression.
- A notable association has been observed between periodontal disease and chronic obstructive pulmonary disease (COPD).
Purpose of the Study:
- To investigate the potential relationship between periodontal health and COPD.
- To compare the health status of patients with and without COPD.
Main Methods:
- An observational study design was employed.
- 100 patients were divided into two groups: 50 with COPD and 50 without.
- Gingival Index (GI), Papilla Bleeding Index (PBI), Russell's Periodontal Index (PI), and Periodontal Index for Risk of Infectiousness (PIRI) were used to assess periodontal status.
- Analysis of covariance (ANCOVA) was utilized for statistical analysis.
Main Results:
- After adjusting for age, significant differences in all measured periodontal indices were found between the COPD and non-COPD groups (P<0.001).
- Periodontal indices were significantly higher in the COPD group compared to the non-COPD group.
Conclusions:
- The study confirms a significant association between periodontal disease and COPD.
- Periodontitis is proposed as a potential risk factor contributing to the development of COPD.
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