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Updated: May 24, 2026
09:47
Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
Extranodal non-Hodgkin's lymphoma presenting as gingival mass
B S Manjunatha1, R Gowramma, D Nagarajappa
1Department of Oral Pathology and Microbiology, K M Shah Dental College and Hospital, Vadodara, Gujarat, India.
Journal of Indian Society of Periodontology
|February 28, 2012
Summary
Non-Hodgkin's lymphoma (NHL) can rarely present in the oral cavity, often mistaken for other conditions. Early dental evaluation is crucial for timely diagnosis and improved outcomes in these rare extra-nodal cases.
Area of Science:
- Oncology
- Oral Pathology
Background:
- Non-Hodgkin's lymphoma (NHL) predominantly originates from B lymphocytes.
- NHL commonly manifests as enlarged lymph nodes with systemic symptoms like fatigue and fever.
Observation:
- Extra-nodal NHL occurs in approximately 3% of cases, with the oral cavity being a potential initial site.
- Patients with oral NHL lesions frequently seek initial dental care.
Findings:
- Intraoral NHL is rare, often presenting as a gingival mass.
- The case highlights a misdiagnosis of a gingival lesion as pyogenic granuloma before confirming extra-nodal NHL.
Implications:
- Prompt clinical assessment and diagnostic workup are vital for early detection of oral NHL.
- Delayed diagnosis of intraoral NHL significantly impacts patient morbidity and mortality.
- Dental professionals play a key role in the initial identification of rare oral malignancies.
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