Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Patient-Specific CFD Modeling of Cerebrospinal Fluid Dynamics in Lumbar Spinal Stenosis using Weight-Bearing MRI: Influence of Stenosis Severity and Postural Changes.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

Same author

Culture of 3D bioprinted bone constructs requires an increased fluid dynamic stimulation.

Acta biomaterialia·2022

Same author

Haematocrit heterogeneity in blood flows past microfluidic models of oxygenating fibre bundles.

Medical engineering & physics·2019

Same author

µ-Particle tracking velocimetry and computational fluid dynamics study of cell seeding within a 3D porous scaffold.

Journal of the mechanical behavior of biomedical materials·2017

Same author

A method for coronary bifurcation centerline reconstruction from angiographic images based on focalization optimization.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2017

Same author

2D µ-Particle Image Velocimetry and Computational Fluid Dynamics Study Within a 3D Porous Scaffold.

Annals of biomedical engineering·2016

Same journal

A case of metastatic Wilms' tumour with reversible distortion of mediastinal anatomy - a diagnostic challenge for the echocardiographer.

Images in paediatric cardiology·2019

Same journal

Prominent Crista Terminalis in a Fetus.

Images in paediatric cardiology·2019

Same journal

Back trauma resulting in commotio cordis.

Images in paediatric cardiology·2019

Same journal

Anomalous Origin of Left Coronary Artery - an unusual case.

Images in paediatric cardiology·2019

Same journal

Aorto-left ventricular tunnel: a rare cause of heart failure in the newborn.

Images in paediatric cardiology·2019

Same journal

Rapidly progressing giant aneurysm of right ventricular outflow tract with severe conduit obstruction: Report of two cases.

Images in paediatric cardiology·2019

See all related articles

Search research articles

Related Experiment Video

Updated: May 24, 2026

Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training

Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training

Published on: February 10, 2022

Computational fluid dynamics in paediatric cardiac surgery.

F Migliavacca¹, G Dubini, M de Leval

¹Research Assistant, Bioengineering Department, Politecnico di Milano, Milan, Italy.

Images in Paediatric Cardiology

|February 28, 2012

Summary

This summary is machine-generated.

Computational fluid dynamics (CFD) models complex blood flow in congenital heart defect surgeries. Understanding local geometry

Keywords:

Cavopulmonary connections Computational fluid dynamics Mathematical model Systemic-to-pulmonary shunt

More Related Videos

Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest

Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest

Published on: May 26, 2023

Modeling the Endothelial Glycocalyx Post-Pneumonectomy in a 3D Fluidic Chip - An Approach to Fabricating a Vascular-based Organ-on-Chip System

Modeling the Endothelial Glycocalyx Post-Pneumonectomy in a 3D Fluidic Chip - An Approach to Fabricating a Vascular-based Organ-on-Chip System

Published on: September 16, 2025

Related Experiment Videos

Last Updated: May 24, 2026

Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training

Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training

Published on: February 10, 2022

Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest

Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest

Published on: May 26, 2023

Modeling the Endothelial Glycocalyx Post-Pneumonectomy in a 3D Fluidic Chip - An Approach to Fabricating a Vascular-based Organ-on-Chip System

Modeling the Endothelial Glycocalyx Post-Pneumonectomy in a 3D Fluidic Chip - An Approach to Fabricating a Vascular-based Organ-on-Chip System

Published on: September 16, 2025

Area of Science:

Cardiovascular Engineering
Biomedical Fluid Dynamics
Computational Medicine

Background:

Surgical reconstructions for complex congenital heart defects face postoperative failure due to flow competition.
Improving understanding of global hemodynamics in these patients is crucial for surgical success.

Purpose of the Study:

To investigate local and global hemodynamics in surgical reconstructions for congenital heart defects.
To devise optimal hydraulic designs for surgical connections using advanced modeling techniques.

Main Methods:

Application of computational fluid dynamics (CFD) techniques.
Development of detailed 3D models of surgical connections using the finite element method.
Integration of local fluid dynamics analysis into zero-dimensional lumped-parameter network models of patient circulation.

Main Results:

Analysis of local fluid dynamics within surgical reconstructions.
Incorporation of local flow features into predictive mathematical models.
Demonstration of the significant impact of local geometry on global hemodynamics.

Conclusions:

Local geometric factors critically influence overall hemodynamics after congenital heart defect surgery.
CFD modeling provides valuable insights for optimizing surgical designs to improve patient outcomes.