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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: May 24, 2026

Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue
11:31

Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue

Published on: February 11, 2013

Imaging microcircuit function in healthy and diseased brain.

Olga Garaschuk1

  • 1Dept. of Physiology II, University of Tuebingen, Keplerstrasse 15, 72074 Tuebingen, Germany. olga.garaschuk@uni-tuebingen.de

Experimental Neurology
|February 29, 2012
PubMed
Summary
This summary is machine-generated.

Microglia, the brain's immune cells, interact with neurons and synapses. This review explores advanced imaging techniques to study neural microcircuit function in both health and disease.

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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

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Related Experiment Videos

Last Updated: May 24, 2026

Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue
11:31

Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue

Published on: February 11, 2013

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
08:39

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

Area of Science:

  • Neuroscience
  • Immunology
  • Cell Biology

Background:

  • Neural microcircuits are fundamental to brain computation.
  • Microglia, the brain's resident immune cells, interact with synapses and influence plasticity.
  • Nervous and immune system interactions are critical in brain injury, inflammation, and neurodegeneration.

Purpose of the Study:

  • To review high-resolution imaging techniques for studying microcircuit function.
  • To highlight recent advances in in vivo calcium imaging.
  • To examine neural microcircuit function in health and disease states.

Main Methods:

  • In vivo calcium imaging.
  • High-resolution microscopy.
  • Focus on techniques applicable to neurons, astrocytes, and microglia.

Main Results:

  • Recent advances enable detailed observation of neural microcircuit dynamics.
  • In vivo imaging allows visualization of cellular interactions in real-time.
  • Techniques are being refined to capture complex cellular crosstalk.

Conclusions:

  • Advanced imaging techniques are crucial for understanding neural microcircuits.
  • Studying microglia and astrocytes alongside neurons provides a more complete picture of brain function.
  • These methods offer new insights into neurological disorders.