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[Cyclosporin in dermatology]

D Salomon1, B Halioua

  • 1Clinique de dermatologie, Hôpital cantonal universitaire, Genève.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|October 16, 1990
PubMed

Cyclosporin is a potent immunosuppressive agent with a selective and reversible inhibitory effect on helper T lymphocytes functions mainly interleukin-2 production. Cyclosporin has no myelotoxic, mutagenic or teratogenic effect. The drug is effective in preventing organ rejection, as well as in various auto-immune and inflammatory diseases. In dermatology the drug is extremely effective in psoriasis. Low doses (less than 5 mg/kg per day) have to be used to decrease the risk of nephrotoxicity and hypertension.

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