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Published on: January 7, 2022
Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate
Yukari Fujimoto1, Ambara Rachmat Pradipta, Naohiro Inohara
1Department of Chemistry, Graduate School of Science, Osaka University, Machikaneyama 1-1, Toyonaka, Osaka 560-0043, Japan. yukarif@chem.sci.osaka-u.ac.jp
Abstract:
Covering: up to 2011. This review focuses on the recent revealing of the immunostimulatory bacterial cell wall peptidoglycan (PGN) fragments as Nod1 ligands, especially a newly developed chemical synthesis of the partial structures, fragment structures in the environment and bacterial supernatant, and the immunostimulatory activities of the Nod1 ligands.
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