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Published on: October 25, 2024
MR angiography in tuberculous meningitis.
Jayantee Kalita1, Sreeram Prasad, Pradeep K Maurya
1Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Acta Radiologica (Stockholm, Sweden : 1987)
|February 29, 2012
Summary
Half of tuberculous meningitis patients show MR angiography abnormalities, often linked to infarcts. Early detection through MRA is crucial for managing TBM complications.
Area of Science:
- Neurology
- Radiology
- Infectious Diseases
Background:
- Tuberculous meningitis (TBM) frequently causes infarcts, yet MR angiography (MRA) data is limited.
- Understanding MRA patterns in TBM is essential for diagnosis and management.
Purpose of the Study:
- To investigate the characteristics of MRA abnormalities in TBM patients.
- To identify predictors associated with MRA findings in TBM.
Main Methods:
- Sixty-seven TBM patients underwent clinical, laboratory, MRI, and MRA assessments.
- MRA evaluated intracranial arteries (MCA, ACA, PCA, basilar) for occlusion or stenosis >50%.
- Abnormalities were correlated with clinical, lab, and MRI findings, including exudates, hydrocephalus, tuberculoma, and infarction.
Main Results:
- 50.7% of TBM patients exhibited MRA abnormalities, predominantly in the MCA, PCA, and ICA.
- MRA abnormalities correlated with hydrocephalus and infarction.
- 61.8% of patients with abnormal MRA had corresponding infarcts, with 41.7% developing new infarcts at 3 months.
Conclusions:
- MRA abnormalities are common in TBM, affecting both anterior and posterior circulations.
- MRA findings are associated with infarct development in TBM patients.
- MRA is a valuable tool for assessing cerebrovascular complications in TBM.
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