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Dental agenesis patterns in Crouzon syndrome
Dimitrios Stavropoulos1, Theodosia Bartzela, Peter Tarnow
1Department of Orthodontics, Institute of Odontology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. Dimitrios.Stavropoulos@odontologi.gu.se
Dental agenesis, the congenital absence of teeth, is common in individuals with Crouzon syndrome. This study found a high prevalence and varied patterns of missing teeth in this population.
Area of Science:
- Dentistry
- Medical Genetics
- Oral and Maxillofacial Surgery
Background:
- Dental agenesis can be isolated or part of a syndrome.
- Crouzon syndrome is a craniosynostosis disorder.
- Dental agenesis patterns in Crouzon syndrome are understudied.
Purpose of the Study:
- To investigate dental agenesis prevalence.
- To analyze dental agenesis patterns in Swedish individuals with Crouzon syndrome.
Main Methods:
- Examined panoramic radiographs of 26 individuals with Crouzon syndrome.
- Excluded third molars from analysis.
- Classified agenesis patterns using the tooth agenesis code (TAC).
Main Results:
- 42.3% of individuals had at least one congenitally missing tooth.
- Second premolars were the most frequently absent teeth.
- Identified 11 unique, mostly asymmetric, dental agenesis patterns.
Conclusions:
- Individuals with Crouzon syndrome exhibit a high prevalence of dental agenesis.
- A significant variability in dental agenesis patterns exists.
- Awareness is crucial for orthodontic treatment planning in mixed dentition.
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