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Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells
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Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

Published on: September 28, 2018

Recombinant antibody mixtures; optimization of cell line generation and single-batch manufacturing processes

Søren K Rasmussen1, Lars S Nielsen1, Christian Müller1

  • 1Symphogen A/S, Elektrovej 375, 2800 Lyngby, Denmark.

BMC Proceedings
|March 1, 2012
PubMed
Abstract

No abstract available in PubMed .

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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