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Strategies for adaptation of mAb-producing CHO cells to serum-free medium

A Rita Costa1, M Elisa Rodrigues1, Mariana Henriques1

  • 1IBB-Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, University of Minho, Braga, Portugal.

BMC Proceedings
|March 1, 2012
PubMed
Abstract

No abstract available in PubMed .

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Hybridoma Technology01:31

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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