Related Experiment Video
Updated: May 24, 2026

10:25
Monitoring Protein-Ligand Interactions in Human Cells by Real-Time Quantitative In-Cell NMR using a High Cell Density Bioreactor
Published on: March 9, 2021
Compartmentation and channelling of metabolites in the human cell line AGE1.HN(®)
Jens Niklas1, Volker Sandig2, Elmar Heinzle1
1Biochemical Engineering Institute, Saarland University, 66123 Saarbrücken, Germany.
BMC Proceedings
|March 1, 2012
Abstract
No abstract available in PubMed .
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One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
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One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
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