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In vitro microbiological evaluation of

Vijayakumar Kanagarajan1, Muthuvel Ramanathan Ezhilarasi, Mannathusamy Gopalakrishnan

  • 1Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Annamalainagar 608 002, Tamil Nadu, India. profmgk@yahoo.co.in.

Organic and Medicinal Chemistry Letters
|March 1, 2012
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The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the para position.