Related Experiment Video
Updated: May 24, 2026
07:21
Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
Published on: May 27, 2022
Systematic review of interventions for post-traumatic headache
Thomas K Watanabe1, Kathleen R Bell, William C Walker
1Department of Physical Medicine and Rehabilitation, MossRehab at Elkins Park/Albert Einstein Medical Center, 60 Township Line Rd, Elkins Park, PA 19027, USA. watanabt@einstein.edu
Summary
Post-traumatic headache (PTHA) lacks strong clinical trial evidence for effective treatments. Further high-quality research is crucial for developing evidence-based management and prevention strategies for PTHA.
Area of Science:
- Neurology
- Trauma Care
- Evidence-Based Medicine
Background:
- Headache is a prevalent symptom following traumatic brain injury (TBI).
- Effective management strategies for post-traumatic headache (PTHA) are needed.
- Current literature has gaps in understanding PTHA treatment efficacy.
Purpose of the Study:
- To determine effective interventions for PTHA.
- To develop treatment recommendations for PTHA.
- To identify research gaps and suggest future directions for PTHA management.
Main Methods:
- Systematic review of peer-reviewed studies published since 1985.
- Inclusion of studies on adult and child TBI, whiplash, and postconcussion syndrome.
- Data extraction and quality rating using American Academy of Neurology criteria.
Main Results:
- No Class I or Class II studies were found for PTHA management.
- Limited Class III studies were identified for PTHA.
- One Class I and one Class II study addressed headache in whiplash-associated disorder.
Conclusions:
- There is a lack of robust clinical trial evidence for PTHA treatment.
- Guidelines for PTHA management are based on primary headache categories.
- Well-designed studies are essential to guide PTHA management and prevent chronicity.
Related Concept Videos
01:27Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
01:28Traumatic Brain Injury l: Introduction
DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...