Related Experiment Video
Updated: May 24, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
Published on: August 24, 2018
[The stepped wedge design]
1Leids Universitair Medisch Centrum, afd. Klinische epidemiologie, Leiden, the Netherlands. o.m.dekkers@lumc.nl
Abstract:
Not all questions concerning therapeutic effects in medical research can be answered satisfactorily by standard trials. The stepped wedge cluster design is a special form of randomised study in which an intervention at group level is implemented in stages. The design can be used in situations where randomization at the patient level is inappropriate or impossible and where a stepped implementation of the experimental intervention is important for ethical, logistic or financial reasons. The time before the experimental intervention is introduced in a cluster is used as control period. The statistical analysis of cluster trials should account for the fact that individuals within clusters may show many similarities. Ethical aspects of stepped wedge design should be considered carefully, especially when obtaining individual informed consent is not possible.
More Related Videos
06:00Four Temporary Waterslide Designs Adapted to Different Slope Conditions to Encourage Child Socialization in Playgrounds
Published on: December 9, 2022
08:31One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes
Published on: September 13, 2018
Related Concept Videos
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs
Wedges
Consider using a wedge to lift a heavy slab. Here, the wedge functions by converting the applied force into a much larger force directed almost perpendicular to the initial force. This...
Design Example: Designing Water Slide
Bernoulli's principle determines the water's velocity along the slide.
Experimental Designs
Factorial Design
Study Design in Statistics
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...