Related Experiment Video

Updated: May 24, 2026

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry
08:07

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Published on: July 26, 2019

Phosphoinositide sensitivity of ion channels, a functional perspective

Nikita Gamper1, Tibor Rohacs

  • 1Institute of Membrane and Systems Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT, Leeds, UK, n.gamper@leeds.ac.uk.

Sub-Cellular Biochemistry
|March 1, 2012
PubMed
Summary

Phosphoinositides, like phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), are crucial for ion channel function. This review explores how PtdIns(4,5)P2 levels regulate diverse ion channels, including K+, Ca2+, and TRP channels.

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