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Nicorandil induced penile ulceration
Michael Kinney1, Declan O'Rourke, Hugh O'Kane
1Dept. of Urology, Belfast City Hospital, Lisburn Road, Belfast. mickinney@gmail.com
The Ulster Medical Journal
|March 1, 2012
Summary
Nicorandil, a medication for angina, can rarely cause penile ulceration. This unusual side effect highlights the importance of monitoring patients for rare complications.
Area of Science:
- Cardiovascular Medicine
- Pharmacology
Background:
- Nicorandil is a potassium channel activator used for angina.
- It is a nicotinamide ester with vasodilatory properties.
Observation:
- This report details an unusual complication associated with Nicorandil use.
- The complication observed was penile ulceration.
Findings:
- Penile ulceration is identified as a rare adverse event of Nicorandil therapy.
- This specific complication has not been widely documented previously.
Implications:
- Clinicians should be aware of this potential side effect when prescribing Nicorandil.
- Further investigation into the mechanism of Nicorandil-induced penile ulceration may be warranted.
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