Related Experiment Video
Updated: May 24, 2026
14:27
Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
Published on: June 26, 2013
Cognitive profiles in heart failure: a cluster analytic approach.
Lindsay A Miller1, Mary Beth Spitznagel, Michael L Alosco
1Department of Psychology, Kent State University, Kent, OH, USA.
Journal of Clinical and Experimental Neuropsychology
|March 2, 2012
Summary
Cognitive impairment in heart failure (HF) patients is not uniform. This study identified three distinct cognitive profiles in older adults with HF, suggesting varied impacts on memory and global cognition.
Area of Science:
- Cardiology
- Neuroscience
- Gerontology
Background:
- Cognitive impairment is frequently observed in individuals with heart failure (HF).
- The specific patterns and heterogeneity of cognitive deficits in HF populations are not well-defined.
- Understanding these cognitive profiles is crucial for effective patient management.
Purpose of the Study:
- To investigate distinct cognitive profiles among older adults diagnosed with heart failure.
- To utilize a cluster analytic approach to identify subgroups based on cognitive function.
- To explore demographic and clinical differences between identified cognitive profiles.
Main Methods:
- The study included 140 older adults diagnosed with heart failure.
- A cluster analysis was employed to group participants based on their cognitive performance.
- Demographic and clinical data were collected and analyzed across clusters.
Main Results:
- Three distinct cognitive profiles were identified: cognitively intact, memory impaired, and globally impaired.
- Significant differences in demographic and clinical characteristics were observed between these clusters.
- The findings highlight the heterogeneity of cognitive impairment in heart failure.
Conclusions:
- Cognitive impairment in heart failure is more diverse than previously assumed.
- Distinct cognitive profiles have implications for tailoring treatment and support strategies for HF patients.
- Further research is warranted to explore the underlying mechanisms and clinical relevance of these profiles.
Related Concept Videos
01:30Heart Failure IV: Classification and Diagnostic Evaluation
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
01:26Heart Failure III: Clinical Manifestations
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
01:29Heart Failure II: Pathophysiology
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
01:27Heart Failure I: Introduction
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
01:17Pathophysiology of Heart Failure
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
01:30Heart Failure VII: Nursing Interventions
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...