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Mediastinal masses in children: experience with 120 cases
Feryal Gun1, Basak Erginel, Aysegul Unüvar
1Department of Pediatric Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. gunferyal@yahoo.com
Pediatric Hematology and Oncology
|March 2, 2012
Summary
This study reviewed 120 pediatric mediastinal masses, finding neurogenic tumors and lymphomas most common. Complete surgical resection is recommended for these rare pediatric tumors, emphasizing a multidisciplinary approach.
Area of Science:
- Pediatric Oncology
- Thoracic Surgery
- Pathology
Background:
- Primary mediastinal masses in children are rare and diverse, originating from various mediastinal structures.
- Diagnosis and management can be challenging due to nonspecific or asymptomatic presentations.
Purpose of the Study:
- To analyze the presentation, histology, and surgical outcomes of primary pediatric mediastinal masses.
- To identify patterns and guide treatment strategies for these rare tumors.
Main Methods:
- Retrospective review of 120 pediatric mediastinal mass cases diagnosed between 1985 and 2011.
- Evaluation included patient demographics, symptoms, tumor origin, surgical intervention, and histopathological findings.
Main Results:
- The median patient age was 5.8 years, with 86 malignant and 34 benign tumors.
- Neurogenic tumors (38.3%) and lymphomas (18.3%) were the most frequent types.
- Common symptoms included cough, dyspnea, and fatigue; 30 patients were asymptomatic.
Conclusions:
- Mediastinal masses in children present a diagnostic challenge, often with nonspecific symptoms.
- Complete surgical resection is crucial for both benign and malignant mediastinal tumors.
- An experienced multidisciplinary team is essential for optimal management of pediatric mediastinal masses.
