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Inflammatory HER2-positive breast cancer

Luc Y Dirix1, Peter B Vermeulen

  • 1Oncology Center, Sint-Augustinus, Antwerp, Belgium.

The Lancet. Oncology
|March 2, 2012
PubMed
Summary

No abstract available in PubMed .

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Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

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