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Updated: May 24, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
Published on: December 20, 2024
Splenectomy as a therapeutic approach in refractory hemophagocytic lymphohistiocytosis
Zhang et al. have reported a case of an adult man with hemophagocytic lymphohistiocytosis (HLH) with an unknown etiology who has achieved a remission of HLH following comprehensive treatment based on splenectomy. In the present communication, the author critically discusses diagnostic and therapeutic issues related to the reported case, and questions utility of splenectomy in the treatment of active HLH.
Zhang et al. have reported a case of an adult man with hemophagocytic lymphohistiocytosis (HLH) with an unknown etiology who has achieved a remission of HLH following comprehensive treatment based on splenectomy. In the present communication, the author critically discusses diagnostic and therapeutic issues related to the reported case, and questions utility of splenectomy in the treatment of active HLH.