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Updated: May 24, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
Published on: September 19, 2016
Reactive arthritis after the intravesical instillation of BCG
Cristina Macía Villa1, Walter Sifuentes Giraldo, Alina Boteanu
1Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, Spain. ccmacia@gmail.com
Abstract:
The intravesical instilation of bacillus Calmette-Guérin (BCG) is a widely used and efficacious procedure for treatment of intermediate to high-grade superficial bladder cancer. The occurrence of osteoarticular side effects is infrequent compared to the number of administrated doses, and reactive arthritis is included within these effects. We present the case of a 54 years old HLA-27 (+) male, who developed reactive arthritis featuring asymmetric olygoarthritis and dactylitis after the second intravesical BCG instillation, which was resolved with administration of Etoricoxib and Isoniazid.
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