Multi-modality in management of primary malignant non-Hodgkin lymphomas of the central nervous system

A retrospective study of nine patients with primary malignant non-Hodgkin lymphomas of the central nervous system was carried out with emphasis on treatment results. Detailed investigations before or during the treatment excluded the presence of extraneural malignant lymphoma. The varying radicality of surgery was followed by radiotherapy, with different doses and techniques occasionally with adjuvant drug treatment. Two patients received chemotherapy. Surgical removal and subsequent radiotherapy as well as the histology were almost identical in patients with longer survival. It was tried to evaluate the prognostic influence of different factors on treatment and survival.