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Post-mastectomy pain syndrome: incidence and risks
Erica Alves Nogueira Fabro1, Anke Bergmann, Blenda do Amaral E Silva
1Federal University of Rio de Janeiro State and National Cancer Institute, Rio de Janeiro, Brazil. efabro@inca.gov.br
Post-mastectomy pain syndrome affects over half of breast cancer patients. Younger women and those undergoing extensive lymph node dissection face a higher risk of developing this chronic neuropathic pain.
Area of Science:
- Oncology
- Pain Medicine
- Surgical Outcomes
Background:
- Post-mastectomy pain syndrome (PMPS) is chronic neuropathic pain persisting over 3 months after breast cancer surgery.
- Understanding PMPS incidence and risk factors is crucial for patient care.
Purpose of the Study:
- To determine the incidence of post-mastectomy pain syndrome.
- To identify risk factors associated with PMPS in breast cancer patients.
Main Methods:
- Prospective cohort study of 174 women undergoing breast cancer surgery.
- Follow-up conducted for 6 months post-operation.
Main Results:
- The incidence of post-mastectomy pain syndrome was 52%.
- Younger women (under 40) had a significantly increased risk (RR=5.23).
- Extensive axillary lymph node dissection (over 15 nodes) also increased risk (RR=2.01).
Conclusions:
- Post-mastectomy pain syndrome is highly prevalent after breast cancer surgery.
- Age and extent of axillary lymph node dissection are significant risk factors for developing PMPS.
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