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Updated: May 24, 2026

A Murine Model of Subarachnoid Hemorrhage

A Murine Model of Subarachnoid Hemorrhage

Published on: November 21, 2013

Putaminal hemorrhages.

Giovanni Ghetti¹

¹Division of Neurosurgery, Santa Maria della Misericordia Hospital, Perugia, Italy. giovanni.ghetti@ospedale.perugia.it

Frontiers of Neurology and Neuroscience

|March 2, 2012

Summary

Hypertensive cerebral hemorrhages in the putamen vary widely, from severe brain bleeds to asymptomatic cases. The severity of bleeding dictates the clinical presentation, evolution, and patient outcomes.

Area of Science:

Neurology
Neurosurgery
Radiology

Background:

The putamen is a frequent location for hypertensive cerebral hemorrhages.
These hemorrhages present with a broad spectrum of clinical manifestations.
Clinical outcomes are significantly influenced by the initial volume of extravasated blood.

Purpose of the Study:

To detail the diverse clinical presentations of putaminal hemorrhages.
To describe both typical and uncommon manifestations of this condition.

Main Methods:

Review of clinical cases of putaminal hemorrhages.
Analysis of patient symptoms, clinical course, and outcomes.
Correlation of clinical findings with hemorrhage magnitude.

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Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

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Last Updated: May 24, 2026

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Main Results:

Putaminal hemorrhages range from massive bleeds affecting cerebral white matter and ventricles to asymptomatic presentations.
Symptoms, clinical progression, and outcomes are directly related to the initial extravasation size.
A spectrum of neurological signs and symptoms is observed.

Conclusions:

The clinical picture of putaminal hemorrhages is highly variable.
Hemorrhage volume is a critical determinant of clinical presentation and prognosis.
Understanding this variability is essential for accurate diagnosis and management.