Related Experiment Video
Updated: May 24, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
Published on: June 13, 2014
Drug-induced PML: a global agenda for a global challenge
M Vinhas de Souza1, B Keller-Stanislawski, K Blake
1Pharmacovigilance and Risk Management Sector, European Medicines Agency, London, UK.
Abstract:
The occurrence of severe adverse events such as progressive multifocal leukoencephalopathy (PML) has the potential to limit the benefits of highly efficacious medicines being developed to fulfill unmet clinical needs across therapeutic areas. Following an Expert meeting in London in July 2011 (http://www.ema.europa.eu/docs/en_GB/document_library/Report/2011/09/WC500111562.pdf), a research agenda, highlighting methodological, clinical, and communication elements, to mitigate the risk and improve the management of drug-induced PML has been agreed upon.
Related Concept Videos
Drug toxicity: Idiosyncratic Reactions
Pharmaceutical Poisoning: Potential Scenarios
Pharmaceutical Poisoning: Treatment Strategies
Encephalitis l: Introduction
Parkinson Disease l: Introduction
Infectious Diseases and Their Occurrence

